To prohibit or forbid something, especially by legal or authoritative order. The government decided to interdict the import of certain hazardous materials.
To intercept and prevent the movement of a prohibited item or person. The coast guard was able to interdict the smuggling operation before it reached the shore.
In military contexts, to impede, disrupt, or destroy an enemy’s lines of communication or supply by firepower or other means before they can be used. Aircraft were deployed to interdict the enemy’s supply convoys along the main highway.