To cause someone to feel embarrassed, ashamed, or humiliated. She was mortified when she realized she had been talking to the wrong person the entire time.
To subdue the body or its needs and desires by self-denial or discipline. He mortified his appetite by fasting for several days.
(of flesh) To decay or become gangrenous; to cause (flesh) to decay. If the wound is left untreated, the tissue may mortify and require surgical removal.