The physical sensation of discomfort or distress caused by injury or illness. She felt a sharp pain in her ankle after twisting it during the run.
Emotional or mental suffering or distress. The pain of losing a loved one can be overwhelming.
A person or thing that is annoying or troublesome. Dealing with the constant noise from the construction site has been a real pain.
Great care, effort, or trouble taken in doing something (usually in the plural). He took pains to ensure the report was accurate.
A penalty or punishment incurred or threatened (chiefly in the phrase "on pain of"). The soldiers were forbidden, on pain of death, to abandon their posts.