A close friend or companion, often used to refer to a godfather or a person with whom one has a strong bond. He has been my compadre since childhood, always there to support me.
In some cultures, a term used to refer to the relationship between the parents and godparents of a child. At the baptism, the parents introduced the godparents as their compadres.
He asked his oldest friend to be the compadre at his daughter’s baptism.