To strike someone with an open hand, especially on the head. The teacher cuffed the student lightly on the head for not paying attention.
To secure or fasten with handcuffs. The police officer cuffed the suspect before leading him to the patrol car.
To fold or roll up the end of a garment, especially a sleeve or trouser leg. On hot days he cuffed his jeans above his ankles.
slang To enter into or commit to a romantic relationship. He didn't want to be cuffed during the summer.