To remove moisture from something, typically in order to preserve it. The company uses a special process to desiccate fruits for long-term storage.
To become completely dry or to lose all moisture. The intense heat caused the riverbed to desiccate over the summer months.
To drain of emotional or intellectual vitality; to make dull or lifeless. The novel's ponderous style tends to desiccate what could have been a gripping story.