To refuse to accept, consider, or submit to something. The committee decided to reject the proposal due to budget constraints.
To dismiss or refuse to acknowledge someone or something. She felt hurt when her ideas were rejected by her colleagues.
To refuse to grant a request or demand. The bank rejected his loan application because of his credit history.
To discard as defective or useless. The quality control team rejected the batch of products due to manufacturing errors.
Of a body: to respond immunologically against (a transplanted organ or tissue), leading to its failure. The patient's immune system rejected the donor kidney within weeks.