To free someone from a criminal charge by a verdict of not guilty. The jury decided to acquit the defendant of all charges.
To conduct oneself or perform in a specified way. She acquitted herself well in the competition, earning praise from the judges.
To discharge or settle (a debt, claim, or obligation); to release someone from a duty, debt, or responsibility (now chiefly archaic). Before retiring, he acquitted all his debts to the firm.